See the production of melatonin peaks in your childhood, remember you could fall asleep anywhere at any time, then it starts to decline after that. 

As you age, you can have as little as 20% of the original melatonin levels that you experienced as a child.[12] Also, most common over the counter medications and drugs can further inhibit melatonin production. [13]  

When your melatonin levels diminish, so can your expectations of restful, nightly sleep. 

The great news is there are numerous studies showing that supplementing with melatonin can help quickly restore your normal sleep pattern.[14,15] 

Unfortunately, just taking melatonin is not that simple. You must be sure that you are taking the right kind of melatonin.  

Have you ever taken melatonin with little to no success, well this information is crucial to know?  

Unfortunately melatonin supplements- like the kind in almost every grocery store- peak in your body about 3-4 hours after you take them. They actually may help you fall asleep but within a few hours, you are up tossing and turning and staring into space, praying to fall back asleep. Or worse the melatonin gave you a reaction never letting you fall asleep in the first place.

In the morning: You wake tired and feel like you did when you didn't take the melatonin supplement.

The answer is to find a supplement with extended-release melatonin. Rather than having your brain flooded with melatonin once you take it, you receive a steady supply of melatonin throughout the night, that why you don't find yourself wide awake at 2 a.m.

A revolutionary study in adults over 55 who received 2 mg of extended-release melatonin before bed for three weeks reported having greater morning alertness, as well as significantly improved quality of sleep. [16]

That's not even the best part, this form of melatonin does not leave you feeling groggy the next day and it can be taken every night as a long-term solution. 

One nightly dose of extended-release melatonin helped another group of older adults fall asleep faster, have better sleep quality and they even reported feeling brighter in the mornings during the entire six-month study. [17] 

In fact, the extra daily melatonin can be outright good for you. There have been multiple studies that show how it provides significant cardiovascular,[18] neuroprotective[19] and anti-inflammatory support.[20]

Bottom line- melatonin is a natural, healthy, scientifically supported solution. Taking the right kind is the "missing key" to unlock the best sleep you have had in years.  

The second key to constant, restorative sleep is an amino acid called gamma-aminobutyric acid, also called GABA.*

GABA is naturally produced by your brain and is a calming agent that helps you disconnect from wakefulness to a sleep state.

GABA releases into the brain to inhibit excitability, alertness and promote relaxation. [2] Boom before you know it, your body relaxes, your thoughts start to ease and you quickly slip into a blissful night of sleep. 

A Harvard Medical School study found that people with chronic sleep issues had 30% lower levels of GABA than people without sleep issues. [21]

In another study, researchers at Columbia University and Indiana University noted reduced levels of GABA in patients who suffer anxiety issues.[22,23]

It's all tied together 

When you are exhausted and your mind is consumed with worry, it is almost impossible to fall asleep. The racing thoughts can have you up all night - especially when your brain is low on one of its biggest relaxing agents. [24]

The understanding of GABA's calming and relaxing role was met with much excitement in the natural and medicinal health world, but like most things, big companies concerned with profits only came into the market and flooded stores with synthetic GABA that was not easily absorbed and did not provide much help.   

Everything changed once a new source of all-natural GABA was developed.

This new form of GABA was produced with a fermentation process like the kind used to develop foods like kimchi. 

This was a revolutionary game-changer. The new form of GABA has scientifically been shown to promote calmness, relaxation and decreases beta-waves in the brain that are linked to nervousness and anxiety.[25] But even better...

In a 7-day observation study, natural GABA was shown to help patients reduce the amount of time it took to fall asleep while increasing sleep quality and the amount of sleep time. Patients also reported having improvements in the way they felt after waking up. [26] 

Another study consisting of 28 days with senior participants showed improvements in sleep habits, morning drowsiness as well as a decrease in urination frequency at nighttime.[27]

We are not done yet. In a third study, it linked a specific form of GABA with the easing of stress in participants. Patients reported feeling calmer and it was reflected in their EEG readings. The reduction in stress was measurably different.[28]  

Ask a doctor, those EEG readings won't lie!

Even more, natural GABA absorbs quickly in your body. This can allow you to start feeling the relaxation response within 5-20 minutes after taking[29]-making it ideal for bedtime. 

That is why GABA is the second "key" to constant, rejuvenating sleep.

Do you want to fall asleep quickly and sleep the entire night, if so follow these 3 little tips:   

1. Find a dual-action melatonin supplement. This first step is vital! The regular melatonin you find in common drug stores helps you get to sleep fairly quickly, but because it only lasts a few hours, you need an extended-release form of melatonin to help you stay asleep the entire night or at least help you get back to sleep with ease. 

2. Only take natural GABA. Most GABA supplements found in stores and online are synthetic and not as effective. The super-absorbable natural form of GABA is great for helping calm the feelings of stress and anxiety with are the enemy of solid sleep.  

3. An appropriate amount of each ingredient is the difference-maker. You want to find a supplement with at least 3mg of melatonin that works with your body to release slowly throughout the night. And for GABA, look for at least 200 mg of the natural form of GABA or GABA producing herbs.   

Concerning questions about nightly and horrendous sleep issues are some of the most common questions I receive from my readers on a regular basis. After listening and answering questions I learned from readers how hard it was to find a natural, non-addictive sleep aid that actually works.   

But after reading and studying so much well research article on melatonin and GABA, I knew there had to be a better answer to sleeping problems. 

So I set out on a mission. I teamed up with board-certified anesthesiologists and herbal supplement experts to see if I could produce a sleep solution backed my research.

1. R.E.M is formulated with research-backed ingredients and doses of the 2 key sleep supports, GABA and melatonin, found to help induce healthy, restorative sleep without groggy, sluggish mornings or harmful side effects that are found with other sleep aids.* 

2. R.E.M provides 3mg of long-lasting melatonin what allows you to fall asleep fast and maintain long-lasting sleep throughout the entire night. 

3. R.E.M contains over 200 mg of Natural GABA and GABA inducing herbs that work as fast-acting calming agents to help you ease your mind from stress and anxiety,  which will help promote healthy all-night sleep.* 

4. Quality is key: R.E.M is USA made and formulated with high-grade premium ingredients that have been inspected and packaged in our FDA-inspected facility here in Oklahoma City and meet and exceeds the USP standards for quality, purity, and disintegration.    

5. Extremely Affordable: R.E.M costs as little as $16.99 per bottle for a full two month's supply. That is an extremely small price for an evolutionary formula that will help you sleep well throughout the night...

AND:

R.E.M SHIPS For FREE with NO RISK: R.E.M is not available in stores. But ships to you free of charge and will reach you within 2-4 business days and has an awesome guarantee! If for any reason you are not happy with the results of R.E.M I will send you a full refund for every dollar. That way you have no risk to try it!

With a lot of supplements, results can take days, weeks even months, before they start to take effect fully in your system. 

But with R.E.M, you should start seeing the immediate benefits of a full night's sleep. Most of our customers say that R.E.M worked for them o the very first night with only 1 capsule.   

There is no doubt on the results you will experience:

✔️ You will slip into all-night sleep faster without restlessness. [23,24] You'll gently relax and sleep, every night.*

✔️ Your stressed mind will stop racing through the night and allow you to enjoy a calm night of sleep.[15,17]

✔️ Your nights will be filled with sound sleep [25,26]- but if you have midnight bathroom runs you will be able to fall asleep quicker than before.

✔️ When you waking up you will feel refreshed and rejuvenated because this natural formula supports the sleep process.[25,26] 

✔️ You will enjoy the benefits of the extra sleep and not worry about taking R.E.M nightly because all our ingredients are all-natural and non-habit forming.[25,26]

✔️ Your overall health will be supported by better sleep.[27,28,29] Improved sleep can help anyone at any age and you will discover the benefits personally. 

Don't forget, every purchase of R.E.M comes with our30-Day Money-Back Guarantee: If for any reason you are not satisfied with your results, We gladly will send you a full refund.

SCIENTIFIC REFERENCES

1. https://www.cdc.gov/media/releases/2016/p0215-enough-sleep.html

2. Bringmann H. Sleep-Active Neurons: Conserved Motors of Sleep. Genetics. 2018 Apr; 208(4): 1279-1289.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887131/

3. https://www.webmd.com/sleep-disorders/features/10-results-sleep-loss#1

4. https://www.webmd.com/sleep-disorders/features/immune-system-lack-of-sleep#1

5. Winer JR, Mander BA. Waking Up to the Importance of Sleep in the Pathogenesis of Alzheimer's Disease. JAMA Neurol. 2018;75(6):654-656. doi:10.1001/jamaneurol.2018.0005

https://jamanetwork.com/journals/jamaneurology/article-abstract/2674274

6. D. Carvalho et al. Association of Excessive Daytime Sleepiness with Longitudinal Β-Amyloid Accumulation in Elderly Persons Without Dementia JAMA Neurology. Vol. 75, June 2018. doi: 10.1001/jamaneurol.2018.0049.
https://jamanetwork.com/journals/jamaneurology/article-abstract/2674279

7. Sprecher KE et al. Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults. Neurology. 2017 Aug 1; 89(5): 445-453.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539733/

8. Shokri-Kojori E et al. Β-Amyloid accumulation in the human brain after one night of sleep deprivation. PNAS April 24, 2018. 115 (17) 4483-4488;
http://www.pnas.org/content/115/17/4483

9. Sprecher KE et al. Amyloid Burden is Associated with Self-Reported Sleep in Non-Demented Late Middle-Aged Adults. Neurobiol Aging. 2015 Sep; 36(9): 2568-2576
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523445/

10. Xie L et al. Sleep Drives Metabolite Clearance From the Adult Brain. Science. 18 Oct 2013: Vol. 342, Issue 6156, pp 373-377
http://science.sciencemag.org/content/342/6156/373

11. http://www.yourhormones.info/hormones/melatonin/

12. Oz M and Roizen M. What happens to our melatonin levels as we age? You: Staying Young: The Owner's Manual for Extending Your Warranty. 2007. Scribner.
https://www.sharecare.com/health/endocrine-system/what-happens-melatonin-aging

13. Murphy PG et al. Nonsteroidal anti-inflammatory drugs alter body temperature and suppress melatonin in humans. Physiol Behav. 1996 Jan;59(1):133-9.
https://www.ncbi.nlm.nih.gov/pubmed/8848472

14. Wurtman RJ. Age-Related Decreases in Melatonin Secretion-Clinical Consequences. The Journal of Clinical Endocrinology & Metabolism, Volume 85, Issue 6, 1 June 2000, Pages 2135-2136
https://academic.oup.com/jcem/article/85/6/2135/2850828

15. Auld F et al. Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders. Sleep Med Rev 2017;34:10-22.
https://www.ncbi.nlm.nih.gov/pubmed/28648359

16. Lemoine P et al. Prolonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects. J Sleep Res 2007;16:372-80.
https://www.ncbi.nlm.nih.gov/pubmed/18036082

17. Wade A et al. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety. BMC Medicine 2010;8:51.
https://www.ncbi.nlm.nih.gov/pubmed/20712869

18. Tengattini S et al. Cardiovascular diseases: protective effects of melatonin. J Pineal Res. 2008 Jan;44(1):16-25.
https://www.ncbi.nlm.nih.gov/pubmed/18078444

19. Alghamdi BS. The neuroprotective role of melatonin in neurological disorders. Neurosci Res. 2018 Jul; 96(7): 1136-1149.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001545/

20. Favero G et al. Melatonin as an Anti-Inflammatory Agent Modulating Inflammasome Activation. Int J Endocrinol. 2017; 2017: 1835195.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643098/

21. Winkelman JW. Reduced brain GABA in primary insomnia: preliminary data from 4T proton magnetic resonance spectroscopy (1H-MRS). Sleep. 2008 Nov;31(11):1499-506.
https://www.ncbi.nlm.nih.gov/pubmed/19014069

22. Kent JM et al. Molecular targets in the treatment of anxiety. Biol Psychiatry. 2002 Nov 15;52(10):1008-30.
https://www.ncbi.nlm.nih.gov/pubmed/12437941/

23. Goddard AW et al. Impaired GABA neuronal response to acute benzodiazepine administration in panic disorder. Am J Psychiatry. 2004 Dec;161(12):2186-93.
https://www.ncbi.nlm.nih.gov/pubmed/15569888/

24. Hu Z et al. Sleep Aids Derived from Natural Products. Biomol Ther. 2018 Jul; 26(4): 343-349.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029681/

25. http://pharmagaba.com/health-benefit-controlling-stress.html

26. Yamatsu A et al. Effect of oral gamma-aminobutyric acid (GABA) administration on sleep and its absorption in humans. Food Sci Biotechnol 2016;25(2):547-51.
http://www.kosfost.or.kr/journal/view.html?uid=9307

27. Horie N et al. Beneficial action of PharmaGaba on sleep disorder and frequent nighttime urination in the elderly.
http://www.pieronline.jp/content/article/0386-3603/41100/985

28. Yoto A et al. Oral intake of gamma-aminobutyric acid affects mood and activities of the central nervous system during stressed condition induced by mental tasks. Amino Acids 2012;43(3):1331-7
https://www.ncbi.nlm.nih.gov/pubmed/22203366

29. http://pharmagaba.com/health-benefit.html

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease and results may vary. Testimonial results are not typical. Customers may have received a gift certificate after submitting their testimonial. The information contained above is for general consumer understanding and education, and should not be considered or used as a substitute for medical advice, diagnosis or treatment. This product is not an alternative to any prescription drug. If you are currently taking a prescription drug, consult your doctor before making any changes. 

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